Stereo-seq应用_时空组学要解决的问题_Stereo-seq技术_STOmics - 华大时空

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华大时空组学技术Stereo-seq已被成功应用到器官发生、胚胎发育、生命演化、脑科学、肿瘤等多个不同领域，证明了其普适性。未来，时空组学有望应用到生命科学与临床研究的各个领域，尤其疾病研究领域，最终为人类健康带来极大的改善。目前，已有150余篇Stereo-seq及其应用成果发表在Cell、Nature、Science等国际顶级学术期刊。

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华大时空文章列表

3D reconstruction of a human Carnegie stage 9 embryo provides a snapshot of early body plan formation

2025-05-08 DOI：10.1016/j.stem.2025.04.007

3D reconstruction of a human Carnegie stage 9 embryo provides a snapshot of early body plan formation

期刊·Cell Stem Cell 物种·人类样本类型·早期胚胎CS9

Quasi-spatial single-cell transcriptome based on physical tissue properties defines early aging associated niche in liver

2025-05-05 DOI：10.1038/s43587-025-00857-7

Quasi-spatial single-cell transcriptome based on physical tissue properties defines early aging associated niche in liver

期刊· Nature Aging 物种·年轻和老年雄性小鼠样本类型·肝脏

Primary cilia in growth plates orchestrate long bone development

2025-05-03 DOI：10.1016/j.fmre.2025.04.014

Primary cilia in growth plates orchestrate long bone development

期刊·Fundamental Research 物种·小鼠样本类型·生长板组织

Tri-omic single-cell mapping of the 3D epigenome and transcriptome in whole mouse brains throughout the lifespan

2025-04-29 DOI：10.1038/s41592-025-02658-7

Tri-omic single-cell mapping of the 3D epigenome and transcriptome in whole mouse brains throughout the lifespan

期刊·Nature Methods 物种·小鼠样本类型·全脑

Single-cell spatial transcriptomics of tertiary lymphoid organ-like structures in human atherosclerotic plaques

2025-04-28 DOI：10.1038/s44161-025-00639-9

Single-cell spatial transcriptomics of tertiary lymphoid organ-like structures in human atherosclerotic plaques

期刊·Nature Cardiovascular Research 物种·小鼠及人样本类型·淋巴器官

Nature子刊 | 首次揭示人类颈动脉斑块中三级淋巴器官！Stereo-seq新突破

2025-04-28 DOI：10.1038/s44161-025-00639-9

Nature子刊 | 首次揭示人类颈动脉斑块中三级淋巴器官！Stereo-seq新突破

期刊·Nature cardiovascular research 物种·人样本类型·颈动脉粥样硬化斑块中三级淋巴器官

Single-nucleus RNA sequencing and spatial transcriptomics reveal the mechanism by which Xiaozhiling injection treats internal hemorrhoids

2025-04-27 DOI：10.4240/wjgs.v17.i4.103494

Single-nucleus RNA sequencing and spatial transcriptomics reveal the mechanism by which Xiaozhiling injection treats internal hemorrhoids

期刊·World J Gastrointest Surg 物种·大鼠样本类型·肛肠

Single-cell multiome reveals root hair-specific responses to salt stress

2025-04-23 DOI：10.1111/nph.70160

Single-cell multiome reveals root hair-specific responses to salt stress

期刊·New Phytologist 物种·无头大白菜样本类型·根尖

Dissecting multilayer cell-cell communications with signaling feedback loops from spatial transcriptomics data

2025-04-22 DOI：10.1101/gr.279857.124

Dissecting multilayer cell-cell communications with signaling feedback loops from spatial transcriptomics data

期刊·Genome Res 物种·人样本类型·新冠肺炎感染的肺组织

Nat. Commun | 多样本时空组学数据联合分析工具重磅发布

2025-04-21 DOI: 10.1038/s41467-025-58079-9

Nat. Commun | 多样本时空组学数据联合分析工具重磅发布

期刊·Nature Communications

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